Overview of Chosen Chemical Compounds and Intermediates

Overview of Chosen Chemical Compounds and Intermediates

Blog Article

one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This really is an impurity linked to bortezomib, a proteasome inhibitor used in the remedy of several myeloma. Its synthesis or research is crucial for making sure the purity and security of the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor while in the synthesis of abiraterone acetate, a drug used in the procedure of prostate cancer by inhibiting androgen production.
Imatinib Intermediate (CAS NO. 152460-ten-1): A critical compound while in the synthesis of imatinib, a drug that targets particular types of cancer, such as Long-term myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats several cancers for example breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): These are intermediates from the synthesis of gemcitabine, an anti-cancer drug. Their examine is very important for optimizing the output method and making sure higher purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-five): Lapatinib is used to deal with breast cancer, and these intermediates are involved with its production.
Fulvestrant Intermediates: Fulvestrant is undoubtedly an estrogen receptor antagonist Employed in the treatment of breast cancer. Numerous intermediates help in the synthesis of this drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-sixteen-nine): This intermediate is Employed in CAS NO. 155405-80-4 the synthesis of paclitaxel, a chemotherapy drug efficient in dealing with cancers for instance ovarian, breast, and lung most cancers.
three. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Employed in the therapy of colorectal cancer and tiny cell lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-82-9): This compound is associated with the synthesis of adamantane derivatives, which have different programs, like antiviral Houses.
Vildagliptin Intermediates: Employed in the creation of vildagliptin, an oral drug for style two diabetic issues that inhibits the enzyme DPP-four to manage blood sugar stages.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is involved with the synthesis of varied gluconic acid derivatives, that happen to be Utilized in foodstuff, pharmaceutical, and industrial apps.
Canagliflozin Intermediate 2: A precursor inside the 4S)-3-Hydroxy-4-phenyl-2-azetidinone synthesis of canagliflozin, a medication employed to manage sort 2 diabetic issues by inhibiting sodium-glucose co-transporter 2 (SGLT2).